SHP2-IN-30 (compound 14i) is an allosteric SHP2 inhibitor with an IC50 of 104 nM. SHP2-IN-30 shows low inhibitory effect on SHP2-PTP. SHP2-IN-30 induces cell apoptosis and arrests the cell cycle at the G0/G1 phase[1].
Molecular Weight:
449.40
Formula:
C21H22Cl2N4OS
Target:
Apoptosis,SHP2
Application Notes:
MCE Product type: Reference compound1
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