YSY01A is a proteasome inhibitor that can suppress cancer cell survival by inducing apoptosis (Apoptosis). Its IC50 values are 51.0 nM for HEK293T, 9.2 nM for A549, 5.2 nM for MCF-7, 8.9 nM for MGC-803, and 35.4 nM for PC-3M cells. Additionally, YSY01A eliminates constitutive STAT3 signaling by downregulating gp130 and JAK2 in human A549 lung cancer cells. YSY01A holds promise for research in the field of cancer therapy[1].
Molecular Weight:
547.45
CAS Number:
[1194235-46-5]
Formula:
C29H38BN5O5
Target:
Interleukin Related,JAK,Proteasome,STAT
Application Notes:
MCE Product type: Reference compound
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