BSO-07 is a ROS/JNK activator with significant anticancer effects, having an IC50 value of 24.81 µM against human breast cancer (BC) cells. BSO-07 induces apoptosis (Apoptosis) and paraptosis by activating JNK and increasing ROS levels, including enhancing the expression of apoptosis-associated proteins such as PARP, Bax, phosphorylated p53, ATF4, and CHOP, while decreasing the levels of anti-apoptotic proteins like Bcl-2, Bcl-xL, and Survivin. BSO-07 holds promise for research in the field of breast cancer[1].
Molecular Weight:
427.94
Formula:
C24H27ClFN3O
Target:
JNK,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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