APTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Krüppel-like factor 4 (KLF4) tumor suppressor[1][2]. APTO-253 has antiarthritic activity[3].
Molecular Weight:
367.38
Purity:
98.86
CAS Number:
[916151-99-0]
Formula:
C22H14FN5
Target:
Apoptosis,c-Myc,KLF
Application Notes:
MCE Product type: Reference compound
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