PROTAC METTL3 degrader 1 is a VHL-based PROTAC METTL3 degrader (DC50: 220 nM in MOLM-13 cells). PROTAC METTL3 degrader 1 inhibits METTL3/14 complex with an IC50 value of 341 nM. PROTAC METTL3 degrader 1 can be used for the research of acute myeloid leukemia and gastric cancer[1].
Molecular Weight:
1054.34
Formula:
C56H77F2N11O5S
Target:
METTL3,PROTACs
Application Notes:
MCE Product type: Reference compound
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