IDO1/TDO-IN-7 (Compound 43b), an isoquinoline derivative, is a potent dual IDO1/TDO inhibitor, with IC50s of 0.31 µM and 0.08 µM, respectively. IDO1/TDO-IN-7 displays acceptable pharmacokinetic profiles and potent antitumor efficacy with low toxicity in B16-F10 tumor model[1].
Molecular Weight:
398.36
Formula:
C17H13F3N2O4S
Target:
Indoleamine 2,3-Dioxygenase (IDO)
Application Notes:
MCE Product type: Reference compound
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