MS7829 is a deubiquitinase-targeting chimera (DUBTAC) that targets cGAS. MS7829 recruits OTUB1 to cGAS, binds covalently to OTUB1, stabilizes the protein abundance of cGAS, and activates the cGAS-STING-IRF3 innate immune signaling pathway in an OTUB1-dependent manner. MS7829 is applicable to cancer-related research[1].
Molecular Weight:
910.95
CAS Number:
[3060519-67-4]
Formula:
C44H57Cl2N9O6S
Target:
Cyclic GMP-AMP Synthase,PROTACs,STING
Application Notes:
MCE Product type: Reference compound
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