HR488B is an efficient HDAC1 inhibitor. HR488B specifically suppressed the growth of CRC cells by inducing cell cycle G0/G1 arrest and apoptosis. HR488B causes mitochondrial dysfunction, reactive oxygen species (ROS) generation, and DNA damage accumulation[1].
Molecular Weight:
488.00
Formula:
C24H26ClN3O4S
Target:
Apoptosis,HDAC,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound1
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