NNRT-IN-2 (compound 7w) is an orally available non-nucleoside reverse transcriptase inhibitor (NNRTI) with broad inhibitory effects on wild-type HIV-1 and mutant strains. NNRT-IN-2 inhibits HIV-1 reverse transcriptase with an EC50 of 22 nM. NNRT-IN-2 is insensitive to CYP and hERG and has good safety and pharmacokinetic characteristics[1].
Molecular Weight:
417.34
CAS Number:
[2999794-78-2]
Formula:
C19H14F3N5O3
Target:
HIV,Reverse Transcriptase
Application Notes:
MCE Product type: Reference compound
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