JE-133 is an optically active isochromane-2H-chromene conjugate. JE-133 exhibits antioxidant and anti-inflammatory activities. JE-133 is a neuroprotective agent that effectively inhibits neuronal oxidative damage associated with PI3K/Akt and MAPK signaling pathways. JE-133 can also inhibit lipopolysaccharide (LPS) (HY-D1056)-induced neuroinflammation by regulating JAK/STAT and Nrf2 signaling pathways[1][2].
Molecular Weight:
412.43
CAS Number:
[2579171-69-8]
Formula:
C23H24O7
Target:
Akt,p38 MAPK,PI3K
Application Notes:
MCE Product type: Reference compound
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