NP3-562 is an orally active NLRP3 Inhibitor. NP3-562 inhibits IL-1beta release in the supernatant of Nigericin (HY-127019)-stimulated THP-1 cells (IC50 = 66 nM), human whole blood (IC50 = 214 nM) and a mouse acute peritonitis model. NP3-562 can be used for the study of acute peritonitis[1].
Molecular Weight:
437.94
Purity:
98.16
CAS Number:
[2409825-32-5]
Formula:
C19H24ClN5O3S
Target:
Interleukin Related,NOD-like Receptor (NLR)
Application Notes:
MCE Product type: Reference compound
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