Bet-in-23 (Compound 23) is a BD2-selective BET inhibitor with an IC50 of 2.9 nM. BET-IN-23 has anticancer activity and can significantly inhibit the proliferation of acute myeloid leukemia (AML) cell lines by inducing G0/G1 arrest and apoptosis in vitro[1].
Molecular Weight:
523.60
CAS Number:
[2953287-57-3]
Formula:
C29H34FN3O5
Target:
Apoptosis,Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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