W6134 is highly potent and selective RORgamma covalent inhibitor with an IC50 of 0.21 µM. W6134 exhibits excellent selectivity for RORgamma over RORalpha, RXRgamma, and ERRgamma. W6134 significantly inhibits RORgamma transcriptional activity W6134 inhibits the proliferation and colony formation and induces apoptosis in castration-resistant prostate cancer cells (CRPC). W6134 can be used for the research of castration-resistant prostate cancers (CRPC)[1].
Molecular Weight:
482.98
Purity:
99.90
CAS Number:
[2983540-55-0]
Formula:
C25H23ClN2O4S
Target:
Apoptosis,ROR
Application Notes:
MCE Product type: Reference compound
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