Cbl-b-IN-16 (compound 31) is an orally active Cbl-b inhibtor with IC50 of 30 nM and induces IL-2 production in Hu-T-cells with EC50 of 230 nM. Cbl-b-IN-16 exhibits antitumor activity[1].
Molecular Weight:
496.53
Formula:
C26H27F3N6O
Target:
E1/E2/E3 Enzyme
Application Notes:
MCE Product type: Reference compound
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