PROTAC HPK1 Degrader-1 (Compound B1) is a potent HPK1 degrader with DC50 value of 1.8 nM. PROTAC HPK1 Degrader-1 inhibits phosphorylation of the SLP76 protein with IC50 value of 496.1 nM. PROTAC HPK1 Degrader-1 is a bona fide HPK1-PROTAC degrader, which provided a potential tool for further HPK1 investigation in TCR signaling[1].
Molecular Weight:
785.84
Purity:
99.70
CAS Number:
[3034182-97-0]
Formula:
C43H43N7O8
Target:
MAP4K,PROTACs
Application Notes:
MCE Product type: Reference compound
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