J-1149 is a potent ALK5 inhibitor, with an IC50 value of 0.017 µM. J-1149 also shows weak p38alpha MAP kinase inhibitory activity, with an IC50 value of 0.435 µM. J-1149 can be used for liver fibrosis research[1].
Molecular Weight:
452.51
CAS Number:
[2883580-95-6]
Formula:
C25H24N8O
Target:
p38 MAPK,TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound
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