HER2-IN-19 (Compound 10e) is a potent inhibitor of HER2 and EGFR with IC50 values of 0.87 respectively and 3.5 nM. HER2-IN-19 has potent inhibitory activity against tumor cells, IC50NCI-N87 = 1.63 nM, IC50BT474= 15.17 nM, IC50BaF3-HER2YVMA = 1.49 nM[1].
Molecular Weight:
541.04
Formula:
C30H29ClN6O2
Target:
EGFR
Application Notes:
MCE Product type: Reference compound1
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