TNIK-IN-9 (Compound 54) is a selective and potent NIK inhibitor, with an IC50 of 1.27 nM. TNIK-IN-9 can inhibit pro-inflammatory cytokines and nitric oxide production. TNIK-IN-9 exhibits significant anti-inflammatory effects, improved mortality, and hepatoprotective effects in sepsis models[1].
Molecular Weight:
487.53
Formula:
C24H21N7O3S
Target:
NF-kappaB
Application Notes:
MCE Product type: Reference compound
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