HPK1-IN-45 (Compound 3) is a HPK1 inhibitor, with an IC50 of 0.3 nM. HPK1-IN-45 inhibits SLP-76 phosphorylation (IC50 = 57.52 nM) and IL-2 release (IC50 = 38 nM). HPK1-IN-45 can be used for the research of cancer[1].
Molecular Weight:
507.58
Formula:
C30H29N5O3
Target:
MAP4K
Application Notes:
MCE Product type: Reference compound
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