Antitumor agent-153 (compound 11b) is an optimized H2A histone ubiquitination inhibitor based on PRT4165 (HY-19817). Antitumor agent-153 inhibits the viability of human osteosarcoma U2OS cells and reduces histone H2A monoubiquitination, exhibiting anticancer activity[1].
Molecular Weight:
324.24
Formula:
C16H8N2O6
Target:
E1/E2/E3 Enzyme
Application Notes:
MCE Product type: Reference compound
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