FGFR-IN-13, CAS [[2962941-25-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-163527
Supplier Catalog Number:
HY-163527
Alternative Catalog Number:
MCE-HY-163527-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
FGFR-IN-13 (compound III-30) is an irreversible covalent fibroblast growth factor receptor (FGFR) inhibitor. FGFR-IN-13 regulates endogenous FGFR1(IC50=0.200.02 nM) and FGFR4(IC50=0.400.03 nM) mediated signaling pathways by inhibiting the expression of key proteins. FGFR-IN-13 inhibits total-PARP and Bcl-2 protein expressions, and promote Cleaved-PARP and Bax protein expressions in a dose-dependent manner. FGFR-IN-13 has significant antitumor activity and oral activity[1].
Molecular Weight:
415.44
CAS Number:
[2962941-25-7]
Formula:
C23H21N5O3
Target:
FGFR
Application Notes:
MCE Product type: Reference compound
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