HN0037 is a selective, orally active helicase-primase inhibitor. HN0037 is primarily metabolized by CYP3A4. HN0037 inhibits HSV replication by targeting the viral helicase-primase complex, which consists of three proteins encoded by the UL5 (helicase), UL52 (primase), and UL8 (a scaffold protein that promotes primer synthesis) genes[1].
Molecular Weight:
428.53
Purity:
99.46
CAS Number:
[2233566-79-3]
Formula:
C20H20N4O3S2
Target:
Cytochrome P450,HSV
Application Notes:
MCE Product type: Reference compound
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