J208 is a dual inhibitor for histone deacetylase (HDAC) and DNA methyltransferase (DNMT). J208 inhibits proliferation of cancer cells, as well as the migration/invasion of triple-negative breast cancer (TNBC) cells. J208 induces apoptosis, arrests the cell cycle at G0/G1 phase. J2008 activates the innate immune signalling pathway in TNBC, by inducing the expression of endogenous retroviruses (ERVs)[1].
Molecular Weight:
412.44
CAS Number:
[2116468-11-0]
Formula:
C20H24N6O4
Target:
Apoptosis,DNA Methyltransferase,HDAC
Application Notes:
MCE Product type: Reference compound
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