TYM-3-98 is a selective inhibitor for PI3Kdelta, with an IC50 of 7.1 nM. TYM-3-98 inhibits proliferationso of B-lymphoma cells. TYM-3-98 inhibits PI3K/AKT/mTOR signaling pathway through induction of apoptosis. TYM-3-98 exhibits good pahrmacokinetic characters and antitumor efficacy in mouse/rat model, without significant toxicity[1].
Molecular Weight:
592.04
CAS Number:
[2820244-59-3]
Formula:
C28H23ClFN7O3S
Target:
Apoptosis,PI3K
Application Notes:
MCE Product type: Reference compound
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