SPP-002 is a ST6GAL1 inhibitor with a human IC50 of 16.7 µM. SPP-002 selectively inhibits N-glycan sialylation over O-glycan sialylation and binds strongly to the enzyme active site. SPP-002 suppresses expression of signaling proteins in the integrin/FAK/paxillin pathway. SPP-002 can be used for the research of triple negative breast cancer metastasis[1].
Molecular Weight:
480.74
Purity:
98
CAS Number:
[3067911-81-0]
Formula:
C24H41KO5S
Target:
Sialyltransferase
Application Notes:
MCE Product type: Reference compound
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