SPP-002 is a sulfate analogue that acts as a potential Sialyltransferase (ST) inhibitor. SPP-002 selectively inhibits n-glycosialylation with inhibition at least an order of magnitude greater than that of unmodified parental cholic acid (LCA). SPP-002 reduces tumor cell migration and invasion by inhibiting the integrin /FAK/Paxillin signaling pathway. SPP-002 can be used in the study of tumor metastasis[1].
Molecular Weight:
480.74
Purity:
98
Formula:
C24H41KO5S
Target:
Sialyltransferase
Application Notes:
MCE Product type: Reference compound
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