BIIB129 is a covalent, selective, small molecule inhibitor of Brutons tyrosine kinase (BTK) capable of penetrating the blood-brain barrier. BIIB129 inhibits the activity of BTK by covalently binding to Cys481 in BTK, thereby affecting the function of B cells and myeloid cells. BIIB129 can be used in multiple sclerosis (MS) research[1].
Molecular Weight:
366.42
Purity:
99.54
CAS Number:
[2770960-52-4]
Formula:
C19H22N6O2
Target:
Btk
Application Notes:
MCE Product type: Reference compound
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