SpiD3, a spirocyclic dimer, is an anticancer agent. SpiD3 markedly inhibits malignant B-cell proliferation and suppressed NF-kappaB activation independent of TME-associated stimuli. SpiD3 induces apoptosis and inhibits protein synthesis in chronic lymphocytic leukemia cells. SpiD3 can be used for study of chronic lymphocytic leukemia (CLL)[1].
Molecular Weight:
470.47
Purity:
98.24
CAS Number:
[3033533-25-1]
Formula:
C27H22N2O6
Target:
Apoptosis,NF-kappaB
Application Notes:
MCE Product type: Reference compound
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