PROTAC AKR1C3 degrader-1 (compound 5) is a potent AKR1C3 PROTAC degrader. PROTAC AKR1C3 degrader-1 decreases the protein expression of AKR1C3, AKR1C1/2, and ARv7. PROTAC AKR1C3 degrader-1 has the potential for the research of prostate cancer. (Blue:ubiquitin E3 ligase cereblon ligand (HY-A0003), Black: linker (HY-163647), Pink: AKR1C3 inhibitor (HY-163610))[1].
Molecular Weight:
841.86
Formula:
C45H43N7O10
Target:
Aldose Reductase,PROTACs
Application Notes:
MCE Product type: Reference compound
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