Anticancer agent 221 (Compound 4h) is an orally active anticancer agent and an antioxidant agent. Anticancer agent 221 exhibits cytotoxicity to cancer cells A549 (IC50=22.09 µg/mL) and MCF-7 (IC50=6.40 µg/mL), and induces apoptosis. Anticancer agent 221 exhibits antioxidant efficacy with an IC50 of 42.46 µM in DPPH experiment. Anticancer agent 221 exhibits antitumor efficacy against breast cancer in mouse models[1].
Molecular Weight:
351.25
Formula:
C17H9F4NO3
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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