Briciclib, CAS [[865783-99-9]]

Product Overview

• Article Name: Briciclib, CAS [[865783-99-9]]
• Biozol Catalog Number: MCE-HY-16366
• Supplier Catalog Number: HY-16366
• Alternative Catalog Number: MCE-HY-16366-10MMX1ML,MCE-HY-16366-5MG,MCE-HY-16366-100MG,MCE-HY-16366-25MG,MCE-HY-16366-1MG,MCE-HY-16366-50MG,MCE-HY-16366-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: ON 014185

Product Description

Briciclib (ON 014185) is a eukaryotic translation initiation factor 4E (eIF4E) inhibitor. Briciclib exhibits broad-spectrum anti-cancer activity, including in mantle cell leukemia, breast cancer, gastric cancer, and esophageal cancer cells. Briciclib reduces the expression of cyclin D1 and c-Myc, and enhances the expression of P53 and Cleaved Caspase 3 pro-apoptotic proteins. Briciclib can be used for the study of hematological system tumors and solid tumors[1].

Product Properties

• Molecular Weight: 474.42
• Purity: 99.45
• CAS Number: [865783-99-9]
• Formula: C19H23O10PS
• Target: Apoptosis,Caspase,CDK,c-Myc,Eukaryotic Initiation Factor (eIF),MDM-2/p53

Application Notes

• Application Notes: MCE Product type: Reference compound1