BR-cpd7 is a PROTAC degrader for fibroblast growth factor receptor FGFR1/2 with DC50 of 10 nM. BR-cpd7 arrests cell cycle, inhibits proliferations of FGFR1/2 aberrant activated tumor cells. (Pink: ligand for target protein FGFR-IN-12 (HY-160013), Black: linker, Blue: ligand for E3 ligase Thalidomide-NH-CH2-COOH (HY-131717))[1]
Molecular Weight:
928.82
Purity:
98.01
Formula:
C44H47Cl2N11O8
Target:
FGFR,PROTACs
Application Notes:
MCE Product type: Reference compound
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