UR778Br targets the GTPase-activating protein-related domain (GRD domain) of IQGAP1 proteins. UR778Br inhibits the proliferation of human acute myeloid leukemia (AML), arrests the cell cycle at the G2/M phase, and induces apoptosis. UR778Br inhibits colony formation of primary and AML cells, without significant impacts on normal bone marrow cells[1].
Molecular Weight:
418.28
Purity:
99.33
CAS Number:
[866127-80-2]
Formula:
C20H20BrNO4
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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