EGFR/DHFR-IN-1 (Compound 10e) is a dual inhibitor of EGFR and DHFR with IC50s of 0.151 and 0.541 µM, respectively. EGFR/DHFR-IN-1 arrests the cell cycle at both G0-G1 and S phases[1].
Molecular Weight:
514.62
Formula:
C24H26N4O5S2
Target:
Dihydrofolate reductase (DHFR) ,EGFR
Application Notes:
MCE Product type: Reference compound
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