SIC-19 is a SIK2 inhibitor and promotes SIK2 protein degradation via the ubiquitination pathway. SIC-19 inhibits cancer cell growth and sensitizes cells to PARP inhibitors (Such as Olaparib (HY-10162)), as well as in ovarian cancer organoids and xenograft models[1].
Molecular Weight:
574.67
Purity:
98
CAS Number:
[713112-69-7]
Formula:
C29H26N4O5S2
Target:
Salt-inducible Kinase (SIK)
Application Notes:
MCE Product type: Reference compound1
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