Antitumor agent-172 (Compound 28) is an inhibitor for beta-catenin/BCL9 interaction with IC50 of 3.92 µM. Antitumor agent-172 exhibits high affinity to beta-catenin with Kd of 82 nM. Antitumor agent-172 activates T cells, promotes antigen presentation, and exhibits antitumor efficacy and good pharmacokinetic characteristics in mouse models[1].
Molecular Weight:
670.84
Purity:
98.51
CAS Number:
[3027905-74-1]
Formula:
C37H50N8O4
Target:
beta-catenin
Application Notes:
MCE Product type: Reference compound
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