Pyruvate Carboxylase-IN-5 (compound 6m) is a pyruvate carboxylase inhibitor with high selectivity and permeability. Pyruvate carboxylase is a mitochondrial enzyme that catalyzes the carboxylation of pyruvate to oxaloacetate, a process that plays an important role in maintaining steady-state levels of Krebs cycle intermediates, which are precursors for the synthesis of biomacromolecules such as amino acids, fatty acids, and glucose[1].
Molecular Weight:
294.24
Purity:
98.92
CAS Number:
[3047101-14-1]
Formula:
C13H11FN2O5
Target:
Pyruvate Carboxylase (PC)
Application Notes:
Reference compound
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