Pacritinib (SB1518) is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). Pacritinib also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM).
Molecular Weight:
472.58
Purity:
99.93
CAS Number:
[937272-79-2]
Formula:
C28H32N4O3
Target:
FLT3,JAK
Application Notes:
MCE Product type: Reference compound1
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