PRMT5-MTA-IN-1, CAS [[3048425-88-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-163799
Supplier Catalog Number:
HY-163799
Alternative Catalog Number:
MCE-HY-163799-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PRMT5-MTA-IN-1 (Compound A9a) is an inhibitor for protein arginine methyltransferase PRMT5-MTA. PRMT5-MTA-IN-1 inhibits the proliferation of colorectal cancer cell HCT116 wildtype and MTAP del mutant, with an IC50 of 16 nM and 2.47 µM. PRMT5-MTA-IN-1 exhibits good liver microsomal stability and film permeability. PRMT5-MTA-IN-1 exhibits good pharmacokinetic characteristics in CD-1 mice[1].
Molecular Weight:
449.40
CAS Number:
[3048425-88-0]
Formula:
C22H19F4N3O3
Target:
Histone Methyltransferase
Application Notes:
Reference compound
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