Pacritinib-d8 (SB1518-d8) is the deuterium labeled Pacritinib (HY-16379). Pacritinib (SB1518) is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). Pacritinib also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM).
Molecular Weight:
476.60
Purity:
98.42
Formula:
C28H28D4N4O3
Target:
FLT3,Isotope-Labeled Compounds,JAK
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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