PD-1/PD-L1-IN-49 (compound 1c) is a potent inhibitor of PD-1/PD-L1, with the IC50 of 77 nM. PD-1/PD-L1-IN-49 activates Jurkat T cells, reflecting successful blockade of the PD-1/PD-L1 immune checkpoint[1].
Molecular Weight:
492.57
Formula:
C27H32N4O5
Target:
PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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