YX862 is a selective HDAC8 PROTAC degrader and induces the degradation of HDAC8 with maximum degradation > 95% at 250 nM in MDA-MB-231 cells(Sturcture Note:(Blue: VHL E3 ligand (HY-112078), Black: linker,Pink: HDAC8 inhibitor (HY-163846))[1].
Molecular Weight:
873.20
Formula:
C48H72N8O5S
Target:
HDAC,PROTACs
Application Notes:
Reference compound
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