LSD1-IN-33 (7d), an orally active LSD1 inhibitor with an IC50 of 4.51 nM, alleviates Ang II-induced NRCFs activation in vitro and reducing pathological myocardial remodeling in TAC-induced cardiac remodeling and heart failure in vivo[1].
Molecular Weight:
370.35
Formula:
C19H16F2N4O2
Target:
Histone Demethylase
Application Notes:
Reference compound
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