VEGFR-IN-5 (compound 9k) is a potent inhibitor of VEGFR2, with the IC50 of 8.4 nM and an acceptable oral bioavailability. VEGFR-IN-5 inhibits migration and invasion of human umbilical vein endothelial cells (HUVEC) cells and induces apoptosis[1].
Molecular Weight:
609.04
Formula:
C31H28ClF3N6O2
Target:
VEGFR
Application Notes:
Reference compound
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