PF-07853578 is an orally active PNPLA3 modulator. PF-07853578 significantly reduces human PNPLA3-I148M protein levels and effectively decreases hepatic triglyceride content by reducing this mutant protein. PNPLA3 degrader-1 can be used in the research of liver cirrhosis and hepatocellular carcinoma[1][2].
Molecular Weight:
408.85
Purity:
99.08
CAS Number:
[3036158-98-9]
Formula:
C16H19ClF2N2O4S
Target:
PNPLA3
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted