Phenformin (1-phenethylbiguanide) is an orally active antidiabetic and anticancer agent. Phenformin has an incidence of associated lactic acidosis. Phenformin acts through acting AMPK activation and blocking mTOR pathway. Phenformin is also a substrate of P-glycoprotein (P-gp), and an OXPHOS inhibitor. Phenformin induces cancer cell apoptosis[1][2].
Molecular Weight:
205.26
Purity:
99.72
CAS Number:
[114-86-3]
Formula:
C10H15N5
Target:
AMPK,Apoptosis,Mitochondrial Metabolism
Application Notes:
Reference compound
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