SIRT3 activator 2 (compound 2a) is a SIRT3 activator. SIRT3 activator 2 improved the thermal stability of SIRT3 in SH-SY5Y cells, indicating that it can directly bind to SIRT3, has SIRT3 dependency in SH-SY5Y to clear alpha-Syn. SIRT3 activator 2 improves motor function in Parkinson mice, preventing Parkinson (DA) neuron loss in the substantia nigra in a dose-dependent manner[1].
Molecular Weight:
492.50
Purity:
98.94
CAS Number:
[3061491-60-6]
Formula:
C22H24N2O9S
Target:
Sirtuin
Application Notes:
Reference compound
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