Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B exerts antitumor activities mediated through the inhibition of pre-mRNA splicing. Pladienolide B induces apoptosis[1][2][3].
Molecular Weight:
536.70
Purity:
99.20
CAS Number:
[445493-23-2]
Formula:
C30H48O8
Target:
Apoptosis,SF3B1
Application Notes:
MCE Product type: Reference compound1
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