TLR4-IN-1 (compound 3k) inhibits the cell viability of RAW264.7 with an IC50 of 1.02 µM. TLR4-IN-1 inhibits the release of cytokine TNF-alpha, IL-1beta and IL-6, and exhibits anti-inflammatory efficacy in rats rheumatoid arthritis models[1].
Molecular Weight:
196.20
CAS Number:
[2617578-93-3]
Formula:
C10H12O4
Target:
Toll-like Receptor (TLR)
Application Notes:
Reference compound
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