CDK4-IN-3 (Compound 389) is a potent irreversible cyclin-dependent kinase 4 (CDK4) inhibitor (IC50=25 nM, >10-fold selective over CDK6). CDK4-IN-3 arrests the cell cycle at G1 phase, and induces tumor cell apoptosis. CDK4-IN-3 is promising for research of solid tumors such as breast and lung cancers[1].
Molecular Weight:
481.56
Purity:
98.07
CAS Number:
[3002399-75-6]
Formula:
C26H32FN5O3
Target:
Apoptosis,CDK
Application Notes:
MCE Product type: Reference compound1
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