CDD-1653 is a potent and selective BMPR2 inhibitor (IC50=2.8 nM). CDD-1653 reduces the ability of ATP to bind to the kinase domain of BMPR2, thereby affecting the phosphorylation of SMAD1/5/8 transcription factors, which play a key role in the BMP signaling pathway. CDD-1653 can be used to study diseases related to the BMP signaling pathway[1].
Molecular Weight:
454.50
Purity:
99.38
CAS Number:
[3034216-44-6]
Formula:
C21H22N6O4S
Target:
TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound1
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